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  4. NLRP9 Protein, Human (sf9, His, Strep)

NLRP9 Protein, Human (sf9, His, Strep) is the recombinant human-derived NLRP9, expressed by sf9 insect cells , with Strep, His labeled tag. ,

For research use only. We do not sell to patients.

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Description

NLRP9 Protein, Human (sf9, His, Strep) is the recombinant human-derived NLRP9, expressed by sf9 insect cells , with Strep, His labeled tag. ,
Background

NLRP9 serves as the sensor component of the NLRP9 inflammasome, playing a pivotal role in innate immunity and inflammation. Upon detecting pathogens such as rotavirus, it initiates the assembly of the inflammasome polymeric complex composed of NLRP9, PYCARD, and CASP1. The recruitment of proCASP1 to the inflammasome facilitates its activation, leading to CASP1-mediated maturation and extracellular release of IL1B and IL18. These active cytokines trigger inflammatory responses. Inflammasomes can also induce pyroptosis, an inflammatory form of programmed cell death. NLRP9 inflammasome activation may be initiated by DHX9's interaction with viral double-stranded RNA (dsRNA), showing a preference for short dsRNA segments.
Species

Human
Source

Sf9 insect cells
Tag

Strep;His
Accession

Q7RTR0-1 (Q89-L991)
Gene ID

338321
Protein Length

Partial
Synonyms
NALP9; NOD6; PAN12
Predicted Molecular Mass
105.8 kDa
Purity

Greater than 80% as determined by reducing SDS-PAGE
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

NLRP9 Protein, Human (sf9, His, Strep) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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NLRP9 Protein, Human (sf9, His, Strep)
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