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  4. NLRP2 Protein, Human (sf9)

NLRP2 Protein, Human (sf9) is the recombinant human-derived NLRP2, expressed by sf9 insect cells , with tag Free labeled tag. ,

For research use only. We do not sell to patients.

Surface Plasmon Resonance (SPR) Assay Service   Protein Expression Service

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Description

NLRP2 Protein, Human (sf9) is the recombinant human-derived NLRP2, expressed by sf9 insect cells , with tag Free labeled tag. ,
Background

NLRP2 suppresses TNF- and CD40-induced NFKB1 activity at the IKK complex level by inhibiting TNF-triggered NFKBIA degradation. When bound to PYCARD, it activates CASP1, promoting the secretion of mature pro-inflammatory cytokine IL1B. NLRP2 is likely a component of the inflammasome, a protein complex also containing PYCARD, CARD8, and CASP1, which functions to activate pro-inflammatory caspases. by similar: NLRP2 shares mechanistic similarities with other inflammasome components (e.g., NLRP3) in regulating caspase activation and cytokine release during inflammatory responses.
Species

Human
Source

Sf9 insect cells
Tag

Tag Free
Accession

Q9NX02-1 (M1-I1062)
Gene ID

55655
Protein Length

Full Length of Isoform-1
Synonyms
NALP2; NBS1; PAN1; PYPAF2
Predicted Molecular Mass
120.6 kDa
Purity

Greater than 95% as determined by reducing SDS-PAGE
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

NLRP2 Protein, Human (sf9) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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