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  4. NaCT Protein, Human (sf9)

NaCT Protein, Human (sf9) is the recombinant human-derived NaCT, expressed by sf9 insect cells , with tag Free labeled tag. ,

For research use only. We do not sell to patients.

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Description

NaCT Protein, Human (sf9) is the recombinant human-derived NaCT, expressed by sf9 insect cells , with tag Free labeled tag. ,
Background

NaCT is a high-affinity sodium/citrate cotransporter that mediates cellular citrate uptake, playing critical roles in various biochemical pathways. It transports citrate in a Na(+)-dependent manner, preferentially recognizing the trivalent citrate form at physiological pH over the divalent form. NaCT is implicated in multiple metabolic processes including energy production (Krebs cycle), fatty acid synthesis, cholesterol synthesis, glycolysis, and gluconeogenesis. While capable of recognizing succinate as a substrate, its affinity for succinate is considerably lower than for citrate. The transport process is likely electrogenic with a probable stoichiometry of 4 Na(+) per carboxylate, regardless of substrate valence state. Additionally, NaCT contributes to citrate level regulation in the brain (by similar).
Species

Human
Source

Sf9 insect cells
Tag

Tag Free
Accession

Q86YT5-1 (M1-T568)
Gene ID

284111
Protein Length

Full Length of Isoform-1
Synonyms
NACT
Predicted Molecular Mass
63.2 kDa
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

NaCT Protein, Human (sf9) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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