2. Recombinant Proteins
  3. Enzymes & Regulators
  4. MEF2A Protein, Human (sf9, GST)

MEF2A Protein, Human (sf9, GST) is the recombinant human-derived MEF2A, expressed by Sf9 insect cells , with GST labeled tag. ,

For research use only. We do not sell to patients.

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Description

MEF2A Protein, Human (sf9, GST) is the recombinant human-derived MEF2A, expressed by Sf9 insect cells , with GST labeled tag. ,
Background

MEF2A is a transcriptional activator that specifically binds to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes. It is involved in activating various growth factor- and stress-induced genes and plays critical roles in skeletal and cardiac muscle development, neuronal differentiation, and survival. Through the p38 MAPK signaling pathway, MEF2A regulates cell growth, survival, and apoptosis in muscle-specific or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses NUR77 transcription to promote synaptic differentiation. Additionally, MEF2A associates with chromatin at the ZNF16 promoter.
Species

Human
Source

Sf9 insect cells
Tag

GST
Accession

Q02078-1 (M1-T507)
Gene ID

4205
Protein Length

Full Length of Isoform-1
Synonyms
MEF2
Predicted Molecular Mass
95 kDa
Purity

Greater than 90% as determined by reducing SDS-PAGE
Documentation
Handling Instructions (2659 KB)

MEF2A Protein, Human (sf9, GST) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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