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  4. KCNA3 Protein, Human (HEK293)

KCNA3 Protein, Human (HEK293) is the recombinant human-derived KCNA3, expressed by HEK293 , with tag Free labeled tag. ,

For research use only. We do not sell to patients.

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Description

KCNA3 Protein, Human (HEK293) is the recombinant human-derived KCNA3, expressed by HEK293 , with tag Free labeled tag. ,
Background

KCNA3 is a voltage-gated potassium channel that opens in response to membrane potential changes, allowing potassium ion flux along their electrochemical gradient. The channel exhibits time-dependent gating with slow inactivation kinetics (By similar). It plays a crucial role in rapid repolarization of fast-spiking neurons in the brain (By similar). KCNA3 can assemble into functional homotetrameric channels or form heterotetramers with varying proportions of KCNC2 and potentially other family members (By similar), contributing to sustained high-frequency firing of brief action potentials in pallidal neurons (By similar).
Species

Human
Source

HEK293
Tag

Tag Free
Accession

P48547-1 (M1-I511)
Gene ID

3746
Protein Length

Full Length of Isoform-1
Synonyms
Voltage-gated potassium channel KCNC1; NGK2; Potassium voltage-gated channel subfamily C member 1; Voltage-gated potassium channel subunit Kv3.1; Voltage-gated potassium channel subunit Kv4; KCNC1; Homo sapiens; Human; Ion channel; Potassium channel; Voltage-gated channel
Predicted Molecular Mass
58.7 kDa
Purity

Greater than 80% as determined by reducing SDS-PAGE
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

KCNA3 Protein, Human (HEK293) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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