2. Recombinant Proteins
  3. Enzymes & Regulators
  4. Hydrolases (EC 3)
  5. HTRA3 Protein, Human (His)

HTRA3 Protein, Human (His) is the recombinant human-derived HTRA3, expressed by E. coli , with His labeled tag. ,

For research use only. We do not sell to patients.

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Description

HTRA3 Protein, Human (His) is the recombinant human-derived HTRA3, expressed by E. coli , with His labeled tag. ,
Background

HTRA3 is a serine protease that cleaves beta-casein/CSN2 and several extracellular matrix (ECM) proteoglycans, including decorin/DCN, biglycan/BGN, and fibronectin/FN1. It potentially inhibits signaling mediated by TGF-beta family proteins, likely indirectly through the degradation of these ECM proteoglycans (by similarity). This protein may function as a tumor suppressor. In vitro studies suggest it negatively regulates trophoblast invasion during placental development, with possible in vivo relevance. Additionally, HTRA3 might play roles in ovarian development, granulosa cell differentiation, and luteinization.
Species

Human
Source

E. coli
Tag

His
Accession

P83110-1 (Q132-K353)
Gene ID

94031
Protein Length

Partial
Synonyms
PRSP
Predicted Molecular Mass
27 kDa
Purity

Greater than 90% as determined by reducing SDS-PAGE
Documentation
Handling Instructions (2659 KB)

HTRA3 Protein, Human (His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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HTRA3 Protein, Human (His)
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