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  4. HSCB Protein, Human (His, Strep)

HSCB Protein, Human (His, Strep) is the recombinant human-derived HSCB, expressed by E. coli , with Strep, His labeled tag. ,

For research use only. We do not sell to patients.

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Description

HSCB Protein, Human (His, Strep) is the recombinant human-derived HSCB, expressed by E. coli , with Strep, His labeled tag. ,
Background

HSCB acts as a co-chaperone in mitochondrial iron-sulfur cluster assembly, facilitating the incorporation of iron-sulfur clusters into SDHB, the iron-sulfur protein subunit of succinate dehydrogenase involved in mitochondrial complex II. It is recruited to SDHB via interaction with SDHAF1, which first binds SDHB and then recruits the iron-sulfur transfer complex (composed of HSC20, HSPA9, and ISCU) through direct binding to HSC20. HSCB also plays an essential role in hematopoiesis (by similar).
Species

Human
Source

E. coli
Tag

Strep;His
Accession

Q8IWL3 (M1-L235)
Gene ID

150274
Protein Length

Full Length
Synonyms
DNAJC20; HSC20
Predicted Molecular Mass
30.6 kDa
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

HSCB Protein, Human (His, Strep) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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HSCB Protein, Human (His, Strep)
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