FGF-9 Protein, Canine (HEK293, mFc)

FGF-9 Protein, Canine (HEK293, mFc) is the recombinant canine-derived FGF-9 protein, expressed by HEK293, with N-mFc tag.

The FGF-9 Protein, belonging to the fibroblast growth factor (FGF) family, exhibits broad mitogenic and cell survival activities, participating in various biological processes such as embryonic development, cell growth, morphogenesis, tissue repair, and tumor growth and invasion. Originally identified as a secreted factor with growth-stimulating effects on cultured glial cells, this protein is predominantly produced by neurons in the nervous system, suggesting its importance in glial cell development. The expression of the mouse homolog of FGF-9 is contingent on Sonic hedgehog (Shh) signaling, and its absence in mice led to a male-to-female sex reversal phenotype, indicating a role in testicular embryogenesis. Noteworthy is the biased expression of FGF-9, with elevated levels detected in the kidney (RPKM 6.4), adrenal (RPKM 2.1), and 10 other tissues, underscoring its potential significance in various physiological contexts across multiple organs.

Canine

HEK293

N-mFc

NP_002001.1 (L4-S208)

2254

Full Length of Mature Protein

Approximately 50 kDa,based on SDS-PAGE under reducing conditions.

Greater than 75% as determined by reducing SDS-PAGE..

<1 EU/μg, determined by LAL method.