2. Recombinant Proteins
  3. FGF-20 Protein, Mouse (His)

FGF-20 Protein, Mouse (His) is the recombinant mouse-derived FGF-20 protein, expressed by E. coli, with N-6*His tag.

For research use only. We do not sell to patients.

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  • Biological Activity

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Description

FGF-20 Protein, Mouse (His) is the recombinant mouse-derived FGF-20 protein, expressed by E. coli, with N-6*His tag.
Background

FGF-20 protein serves as a neurotrophic factor crucial for the regulation of central nervous system development and function. Operating as a homodimer, it interacts with specific receptors, namely FGFR2 and FGFR4. The binding affinity between fibroblast growth factors (FGFs) and their receptors is enhanced by heparan sulfate glycosaminoglycans, acting as coreceptors in this intricate signaling process.
Species

Mouse
Source

E. coli
Tag

N-6*His
Accession

Q9ESL9 (M1-T211)
Gene ID

80857
Molecular Construction
N-term
6*His
FGF-20 (M1-T221)
Accession # Q9ESL9
C-term
Protein Length

Full Length
Synonyms
Fibroblast growth factor 20; FGF20; Fgf20
AA Sequence

MAPLTEVGAFLGGLEGLSQQVGSHFLLPPAGERPPLLGERRGALERGARGGPGSVELAHLHGILRRRQLYCRTGFHLQILPDGTVQGTRQDHSLFGILEFISVAVGLVSIRGVDSGLYLGMNDKGELYGSEKLTSECIFREQFEENWYNTYSSNIYKHGDTGRRYFVALNKDGTPRDGARSKRHQKFTHFLPRPVDPERVPELYKDLLMYT

Predicted Molecular Mass
27.7 kDa
Molecular Weight

Approximately 27.7 kDa,based on SDS-PAGE under reducing conditions.
Structure/Form
Monomer
Purity

Greater than 85% as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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FGF-20 Protein, Mouse (His)
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