FBLN1 Protein, Human (HEK293, His, Myc)

FBLN1 Protein, Human (HEK293, His, Myc) is the recombinant human-derived FBLN1, expressed by HEK293 , with N-10*His, C-Myc labeled tag.

FBLN1 is a protein incorporated into fibronectin-containing matrix fibers within the extracellular matrix (ECM), potentially playing roles in cell adhesion and migration along ECM protein fibers. It contributes to certain developmental processes and the supramolecular organization of ECM architecture, particularly in basement membranes. Evidence suggests FBLN1 may act as a tumor suppressor, with implications in cellular transformation and tumor invasion. Additionally, its fibrinogen-binding capability and incorporation into clots indicate potential functions in haemostasis and thrombosis. by similar: FBLN1 might also significantly modulate the neurotrophic activities of APP, especially soluble APP.

Immobilized Human ITGA5-ITGB1 (HY-P73872) at 2 μg/mL (100 μL/well) can bind Biotinylated Human FBLN1 Protein, the ED₅₀ for this effect is <2.5 μg/mL.

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  Immobilized Human ITGA5-ITGB1 (HY-P73872) at 2 μg/mL (100 μL/well) can bind Biotinylated Human FBLN1 Protein, the ED₅₀ for this effect is 1.950 μg/mL.

Human

HEK293

N-10*His;C-Myc

P23142-1 (D30-F703)

2192

Full Length of Isoform-1 Mature Protein

Approximately 80-100 kDa, due to the glycosylation.

• 
  Greater than 95% as determined by reducing SDS-PAGE.

Lyophilized powder

Lyophilized from a 0.22 μm filtered solution of PBS, 6% Trehalose, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.