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  4. FADD Protein, Human (His)

FADD Protein, Human (His) is the recombinant human-derived FADD, expressed by E. coli , with His labeled tag.

For research use only. We do not sell to patients.

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Description

FADD Protein, Human (His) is the recombinant human-derived FADD, expressed by E. coli , with His labeled tag.
Background

FADD is an apoptotic adapter molecule that recruits caspases CASP8 or CASP10 to activated FAS/CD95 or TNFRSF1A/TNFR-1 receptors. The resulting complex, called the death-inducing signaling complex (DISC), performs proteolytic activation of CASP8. Active CASP8 initiates the subsequent cascade of caspases mediating apoptosis. Additionally, FADD is involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. by similar content includes: FADD's function in DISC and its role in the apoptotic cascade.
Species

Human
Source

E. coli
Tag

His
Accession

Q13158 (M1-S208)
Gene ID

8772
Protein Length

Full Length
Synonyms
MORT1
Predicted Molecular Mass
27 kDa
Purity

Greater than 95% as determined by reducing SDS-PAGE
Documentation
Handling Instructions (2659 KB)

FADD Protein, Human (His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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FADD Protein, Human (His)
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