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  4. HER4 Protein, Human, (HEK293, hFc)

HER4 Protein, Human, (HEK293, hFc) is the recombinant human/rhesus macaque-derived HER4 protein, expressed by HEK293, with C-hFc tag.

For research use only. We do not sell to patients.

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Description

HER4 Protein, Human, (HEK293, hFc) is the recombinant human/rhesus macaque-derived HER4 protein, expressed by HEK293, with C-hFc tag.
Background

ERBB4 is a protein that plays important roles in the development of the central nervous system, neural crest cell migration, and axon guidance. It is also involved in mammary gland differentiation, induction of milk proteins, and lactation.
Species

Human; Rhesus Macaque
Source

HEK293
Tag

C-hFc
Accession

NP_005226.1 (Q26-R649)
Gene ID

2066
Protein Length

Partial
Synonyms
erb-b2 receptor tyrosine kinase 4
Predicted Molecular Mass
96.6 kDa
Molecular Weight

Approximately 117 kDa,based on SDS-PAGE under reducing conditions.
Purity

Greater than 85% as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

HER4 Protein, Human, (HEK293, hFc) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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HER4 Protein, Human, (HEK293, hFc)
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