E/Envelope Protein, Dengue virus 2 (102a.a, P.pastoris, His)

E/Envelope Protein, Dengue virus 2 (102a.a, P.pastoris, His) is the recombinant Virus-derived E/Envelope protein, expressed by P. pastoris, with C-His labeled tag.

E/Envelope acts as a chaperone for the envelope protein E during intracellular virion assembly by masking and inactivating the fusion peptide of envelope protein E. prM is the only viral peptide matured by host furin in the trans-Golgi network, likely to prevent catastrophic activation of viral fusion activity in the acidic Golgi compartment before virion release. prM-E cleavage is inefficient, resulting in many virions being only partially matured. These uncleaved prM may contribute to immune evasion.

Virus

P. pastoris

C-His

AAC59274.1 (G534-G675)

/

Partial

Approximately 17.1 kDa

Greater than 95% as determined by reducing SDS-PAGE.

Solution.

Supplied as a 0.22 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.