2. Recombinant Proteins
  3. Enzymes & Regulators
  4. DPY30 Protein, Human (His)

DPY30 Protein, Human (His) is the recombinant human-derived DPY30, expressed by E. coli , with N-6*His labeled tag.

For research use only. We do not sell to patients.

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Description

DPY30 Protein, Human (His) is the recombinant human-derived DPY30, expressed by E. coli , with N-6*His labeled tag.
Background

DPY30 is a component of the MLL1/MLL complex, involved in the methylation of histone H3 at Lys-4, particularly trimethylation. Histone H3 Lys-4 methylation serves as a specific tag for epigenetic transcriptional activation. It may play a role in histone H3 acetylation. In teratocarcinoma cells, DPY30 is critical for retinoic acid-induced neural lineage differentiation by regulating gene induction and H3 Lys-4 methylation at key developmental loci. It may also have a direct or indirect role in endosomal transport. by similar: Other MLL complex members may share analogous functions.
Species

Human
Source

E. coli
Tag

N-6*His
Accession

Q9C005 (E2-N99)
Gene ID

84661
Molecular Construction
N-term
6*His
DPY30 (E2-N99)
Accession # Q9C005
C-term
Protein Length

Partial
Synonyms
DPY30; HDPY30
Predicted Molecular Mass
12 kDa
Molecular Weight

Approximately 15-20 kDa,based on SDS-PAGE under reducing conditions.
Purity

Greater than 90% as determined by reducing SDS-PAGE
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

DPY30 Protein, Human (His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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DPY30 Protein, Human (His)
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