1. Recombinant Proteins
  2. CAR-T Related Proteins Receptor Proteins
  3. Notch family
  4. Delta-like 3 (DLL3)
  5. Delta-like protein 3/DLL3 Protein, Human (HEK293, Llama Fc)

Delta-like protein 3/DLL3 Protein, Human (HEK293, Llama Fc)

Cat. No.: HY-P704566
Handling Instructions Technical Support

Delta-like protein 3/DLL3 stands out as a key regulator of neurogenesis and cell differentiation. As an inhibitor of primary neurogenesis, DLL3 plays a crucial role in guiding neurons along specific differentiation pathways. Delta-like protein 3/DLL3 Protein, Human (HEK293, Llama Fc) is the recombinant human-derived Delta-like protein, expressed by HEK293, with C-Llama Fc labeled tag.

For research use only. We do not sell to patients.

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Description

Delta-like protein 3/DLL3 stands out as a key regulator of neurogenesis and cell differentiation. As an inhibitor of primary neurogenesis, DLL3 plays a crucial role in guiding neurons along specific differentiation pathways. Delta-like protein 3/DLL3 Protein, Human (HEK293, Llama Fc) is the recombinant human-derived Delta-like protein, expressed by HEK293, with C-Llama Fc labeled tag.

Background

Delta-like protein 3/DLL3 emerges as a key regulator in the intricate landscape of neurogenesis and cellular differentiation. Acting as an inhibitor of primary neurogenesis, DLL3 is believed to play a crucial role in steering neurons along specific differentiation pathways. Its involvement extends beyond neurogenesis, contributing to the formation of somite boundaries during the segmentation of the paraxial mesoderm. Notably, DLL3 exhibits the capability to bind and activate Notch-1 or other Notch receptors, underscoring its significance in orchestrating cellular processes that govern developmental pathways and cellular fate determination.

Species

Human

Source

HEK293

Tag

C-Llama Fc

Accession

Q9NYJ7-1 (A27-L492)

Gene ID

10683

Molecular Construction
N-term
DLL3 (A27-L492)
Accession # Q9NYJ7-1
Llama Fc
C-term
Synonyms
Delta3; DLL3; Pudgy; SCDO1; SCDO1delta3
Predicted Molecular Mass
76.6 kDa.
Molecular Weight

75-85 kDa

Glycosylation
Yes
Purity

Greater than 90% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

Delta-like protein 3/DLL3 Protein, Human (HEK293, Llama Fc) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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  • Dilution Calculator

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
Delta-like protein 3/DLL3 Protein, Human (HEK293, Llama Fc)
Cat. No.:
HY-P704566
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