CSF1R Protein, Mouse (492a.a, HEK293, His)

The CSF1R protein has macrophage colony-stimulating factor receptor activity, homodimerization and protein phosphatase binding, and plays a crucial role in nervous system development and protein phosphorylation regulation. It is located on the cell surface and plasma membrane and is part of the CSF1-CSF1R complex. CSF1R Protein, Mouse (492a.a, HEK293, His) is the recombinant mouse-derived CSF1R protein, expressed by HEK293 , with C-His labeled tag. The total length of CSF1R Protein, Mouse (492a.a, HEK293, His) is 492 a.a., with molecular weight of 66-100 kDa.

CSF1R Protein plays a crucial role in various functions, encompassing macrophage colony-stimulating factor receptor activity, protein homodimerization activity, and protein phosphatase binding activity. Involved in processes such as nervous system development, positive regulation of protein phosphorylation, and general protein phosphorylation, CSF1R is located on the cell surface and plasma membrane and is a constituent of the CSF1-CSF1R complex. The gene is expressed in diverse structures, including the alimentary system, central nervous system, extraembryonic component, genitourinary system, and limb. As the orthologous counterpart to human CSF1R (colony stimulating factor 1 receptor), CSF1R is implicated in human diseases such as adult-onset leukoencephalopathy with axonal spheroids and pigmented glia, as well as renal cell carcinoma. Broad expression is observed across multiple tissues, with significant levels in the spleen adult (RPKM 69.7), placenta adult (RPKM 34.8), and 23 other tissues, underscoring its widespread roles in various physiological contexts.

Mouse

HEK293

C-His

NP_001032948 (A20-S511)

12978  [NCBI]

66-100 kDa

Greater than 95% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.