CNDP2 Protein, Mouse (sf9, His)

CNDP2 Protein, Mouse (sf9, His) is the recombinant mouse-derived CNDP2 protein, expressed by Sf9 insect cells, with C-His tag.

HO-2/HMOX2 protein serves as a catalyst in the oxidative cleavage of heme at the alpha-methene bridge carbon, liberating carbon monoxide (CO) and producing biliverdin IXalpha. This enzymatic process results in the release of the central heme iron chelate as ferrous iron. HO-2/HMOX2 plays a crucial role in the breakdown of heme, facilitating the controlled generation of signaling molecules such as CO and biliverdin. The release of CO, in particular, has various physiological implications, contributing to vascular homeostasis, anti-inflammatory responses, and cellular protection. This enzyme's activity is integral to the regulation of heme metabolism and the maintenance of cellular redox balance.

Mouse

Sf9 insect cells

C-His

NP_075638.2 (M1-N475)

66054

Full Length

MSALKAVFQYIDENQDRYVKKLAEWVAIQSVSAWPEKRGEIRRMMEVAAADVQRLGGSVELVDIGKQKLPDGSEIPLPPILLGKLGSDPQKKTVCIYGHLDVQPAALEDGWDSEPFTLVEREGKLYGRGSTDDKGPVAGWMNALEAYQKTGQEIPVNLRFCLEGMEESGSEGLDELIFAQKDKFFKDVDYVCISDNYWLGKNKPCITYGLRGICYFFIEVECSDKDLHSGVYGGSVHEAMTDLISLMGCLVDKKGKILIPGINDAVAPVTDEEHALYDHIDFDMEEFAKDVGAETLLHSCKKDILMHRWRYPSLSLHGIEGAFSGSGAKTVIPRKVVGKFSIRLVPDMIPEVVSEQVSSYLSKKFAELQSPNKFKVYMGHGGKPWVSDFNHPHYQAGRRALKTVFGVEPDLTREGGSIPVTLTFQEATGKNVMLLPVGSADDGAHSQNEKLNRLNYIEGTKMLAAYLYEVSQLKN

Approximately 50 kDa,based on SDS-PAGE under reducing conditions.

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.