Claudin-6/CLDN6 Protein-VLP, Human (HEK293, solution)

Claudin-6/CLDN6 Protein-VLP, Human (HEK293) is recommended for SPR analysis, animal immunization, ELISA, PK assay. If VLP control is required, it is recommended HY-P702775. May have binding signals with Anti-His antibodies.

The Claudin-6/CLDN6 protein-VLP plays a crucial role in the specific obliteration of the intercellular space in tight junctions. It is involved in maintaining the integrity of the cell barrier, preventing leakage and maintaining cell polarity. Additionally, the protein acts as a receptor for hepatitis C virus (HCV) entry into hepatic cells, facilitating viral infection.

1.Immobilized Human Claudin 6 VLP at 5 μg/mL(100 μl/Well). Dose response curve for AntiClaudin 6 Antibody, mFc Tag with the EC₅₀ of ≤5.5 ng/mL determined by ELISA.
2.Human Claudin 6 VLP immobilized on CM5 Chip can bind Anti-Claudin 6 Antibody with an affinity constant of 0.26 nM as determined in SPR assay (Biacore T200).

Human

HEK293

Tag Free

P56747 (M1-V220)

9074  [NCBI]

Full Length

Approximately 24.5 kDa

Greater than 95% as determined by HPLC.

Solution

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4. Notice: If you need it for immunization, Do Not use any adjuvant.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.