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  4. CDCP1 Protein, Cynomolgus (HEK293, C-His)

CDCP1 Protein, Cynomolgus (HEK293, C-His) is the recombinant cynomolgus-derived CDCP1 protein, expressed by HEK293, with C-His tag.

For research use only. We do not sell to patients.

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Description

CDCP1 Protein, Cynomolgus (HEK293, C-His) is the recombinant cynomolgus-derived CDCP1 protein, expressed by HEK293, with C-His tag.
Background

CDCP1, a cell surface glycoprotein, is a ligand for CD6, a receptor molecule expressed on certain T cells that may play a role in T cell migration and chemotaxis. CDCP1 may lead to autoimmune diseases such as encephalomyelitis, multiple sclerosis and inflammatory arthritis. CDCP1 mediates anti-adhesion and anti-migration by negatively regulating integrin receptors. CDCP1 promotes tumor proliferation and metastasis by activating MAPK/ERK and AKT signaling pathways[1][2][3].
Species

Cynomolgus
Source

HEK293
Tag

C-8*His
Accession

XP_005546930 (F30-T667)
Gene ID

102129146
Protein Length

Extracellular Domain
Synonyms
CUB domain-containing protein 1
AA Sequence

FEIALPRESNITVLIKLGTPTLLAKPCYIVISKRHTTMLSIKPGERILFTFSCQSPENHFVIEIQKNIDCMSGPCPFGEVQLQPSTSLLPTLNRTFIWDVKAHKSIGLELQFSIPRLRQIGPGESCPDGVTYSISGRIDATVVRIGTFCSNGTVSRIKMQEGVKMALHLPWFHPRNVSGFSIANRSSIKRLCIIESVFEGEGSATLMSANYPEGFPEDELMTWQFVIPAHLRASVSFLNFNLSNCERKEERVEYYIPGSTTNPEVFKLEDKQPGNMAGNFNLSLQGCDQDAQNPGILRLQFQVLVQHPQNESNKIYVVDLSNERATSLTIEPRPVKQSRKFVPGCFVCLESRTCSTNLTLTSGSKHKISFLCDNLTRLWMNVEKNISCTDHRYCQRKSYSLQVPSDILHLPVELHDFSWKLLVPKDRLSLVLVPAQKLQQHTHEKPCNTSFSYLVASAIPSQDLYFGSFCPGGSIEQIQVKQNISVTLRTFAPSFRQEASRQGLTVSFIPYFKEEGVFTVTPDTKSKVYLRTPNWDRGLPSLTSVSWNISVPRDQVACLTFFKERTGVVCQTGRAFMIIQEQRTRAEEIFSLDEDALPKPRFHHHSFWVNISNCSPASGKQLDLLFWVTLTPRTVDLT

Predicted Molecular Mass
73.2 kDa
Molecular Weight

Approximately 90-110 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.
Glycosylation
Yes
Purity

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
SDS (251 KB)

COA (221 KB)

Handling Instructions (2659 KB)

CDCP1 Protein, Cynomolgus (HEK293, C-His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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CDCP1 Protein, Cynomolgus (HEK293, C-His)
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