Cadherin-17 Protein, Mouse (HEK293, hFc)

Cadherin-17 protein mediates cell-cell interactions by selectively binding to other cadherin-17 proteins in a homophilic manner. This interaction promotes connections between adjacent cells and helps sort and organize different cell types within the tissue. Cadherin-17 Protein, Mouse (HEK293, hFc) is the recombinant mouse-derived Cadherin-17 protein, expressed by HEK293, with C-hFc labeled tag.

Cadherin-17 is a calcium-dependent cell adhesion protein that plays a crucial role in cell-to-cell interactions. It exhibits a preferential interaction with other cadherin-17 proteins in a homophilic manner, facilitating the connection between neighboring cells. This specific interaction enables cadherin-17 to contribute to the sorting and organization of diverse cell types within tissues. In particular, LI-cadherin, a subtype of cadherin-17, has been implicated in the morphological organization of liver and intestine, suggesting its involvement in the structural arrangement of these organs.

Mouse

HEK293

C-hFc

Q9R100-1 (F26-M786)

12557

Approximately 50 kDa & 110-130 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.

Greater than 90% as determined by reducing SDS-PAGE..

Lyophilized powder.

Lyophilized from 0.22 μm filtered solution of 20 mM Tris, 150 mM NaCl, pH8.0 with trehalose as protectant.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.