1. Recombinant Proteins
  2. Receptor Proteins
  3. Cell Adhesion Molecules (CAMs)
  4. Cadherins
  5. Cadherin-10
  6. Cadherin-10/CDH10 Protein, Human (HEK293, His)

Cadherin-10/CDH10 Protein, Human (HEK293, His)

Cat. No.: HY-P78769
Handling Instructions Technical Support

Cadherin-10/CDH10 is a calcium-dependent cell adhesion molecule in the cadherin family that participates in preferential homophilic interactions and promotes self-association between adjacent cells. This suggests a key role in mediating cell adhesion and may aid in sorting heterogeneous cell types. Cadherin-10/CDH10 Protein, Human (HEK293, His) is the recombinant human-derived Cadherin-10/CDH10 protein, expressed by HEK293 , with C-His labeled tag.

For research use only. We do not sell to patients.

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Description

Cadherin-10/CDH10 is a calcium-dependent cell adhesion molecule in the cadherin family that participates in preferential homophilic interactions and promotes self-association between adjacent cells. This suggests a key role in mediating cell adhesion and may aid in sorting heterogeneous cell types. Cadherin-10/CDH10 Protein, Human (HEK293, His) is the recombinant human-derived Cadherin-10/CDH10 protein, expressed by HEK293 , with C-His labeled tag.

Background

Cadherin-10/CDH10 protein, a member of the cadherin family, operates as a calcium-dependent cell adhesion molecule. Functioning through preferential homophilic interactions, Cadherin-10/CDH10 facilitates self-binding between adjacent cells. This homophilic cadherin engagement suggests a pivotal role in mediating cell adhesion and likely contributes to the intricate process of sorting heterogeneous cell types. Through its calcium-dependent adhesion properties, Cadherin-10/CDH10 is instrumental in establishing selective connections between cells, playing a crucial part in the dynamic regulation of cellular interactions and the organization of tissues.

Species

Human

Source

HEK293

Tag

C-His

Accession

Q9Y6N8 (G55-A613)

Gene ID
Molecular Construction
N-term
CDH10 (G55-A613)
Accession # Q9Y6N8
His
C-term
Protein Length

Extracellular Domain

Synonyms
Cadherin-10; CDH10; T2-cadherin
Molecular Weight

70-95 kDa

Glycosylation
Yes
Purity

Greater than 90% as determined by reducing SDS-PAGE.

Appearance

Lyophilized powder

Formulation

Lyophilized a 0.22 μm filtered solution of PBS, 6% Trehalose, pH 7.4.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Reconstitution

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.

Storage & Stability

Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Documentation

Cadherin-10/CDH10 Protein, Human (HEK293, His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Product Name:
Cadherin-10/CDH10 Protein, Human (HEK293, His)
Cat. No.:
HY-P78769
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