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  4. birA Protein, B. subtilis (His)

birA Protein, B. subtilis (His) is the recombinant birA protein, expressed by E. coli, with His tag.

For research use only. We do not sell to patients.

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Description

birA Protein, B. subtilis (His) is the recombinant birA protein, expressed by E. coli, with His tag.
Background

WBP2 protein functions as a transcriptional coactivator for estrogen and progesterone receptors (ESR1 and PGR) upon hormone activation, binding to ESR1-responsive promoters in the presence of estrogen. It is essential for the coactivation function of YAP1 on PGR activity and synergizes with WBP2 in enhancing PGR activity. Additionally, WBP2 modulates the expression of post-synaptic scaffolding proteins through the regulation of ESR1, ESR2, and PGR. WBP2 interacts with the WW domain of YAP1, WWP1, and WWP2, and also forms interactions with NEDD4. Moreover, it associates with ESR1 and UBE3A, contributing to its role as a transcriptional coactivator in hormone-responsive pathways.
Species

Others
Source

E. coli
Tag

His
Accession

P0CI75 (G66-G325, R124G, E323S, G325R)
Gene ID

939028
Protein Length

Partial
Synonyms
Bifunctional ligase/repressor BirA; Biotin--[acetyl-CoA-carboxylase] ligase; 6.3.4.15; Biotin--protein ligase; Biotin-[acetyl-CoA carboxylase] synthetase; birA; Bacillus subtilis (strain 168); DNA-binding; Ligase; Repressor
Predicted Molecular Mass
30.4 kDa
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

birA Protein, B. subtilis (His) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

  • Specific Activity Calculator

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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birA Protein, B. subtilis (His)
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