2. Recombinant Proteins
  3. Cytokines and Growth Factors Receptor Proteins Enzymes & Regulators
  4. TGF-beta Superfamily Receptor Serine/Threonine Kinases Serine/Threonine Kinase Proteins
  5. Activin/Inhibins Receptor
  6. Activin A Receptor Type 2A (ACTR-IIA)
  7. ACVR2A/Activin RIIA Protein, Human/Cynomolgus (Biotinylated, HEK293, hFc, Avi)

ACVR2A/Activin RIIA Protein, Human/Cynomolgus (Biotinylated, HEK293, hFc, Avi)

Cat. No.: HY-P703995
Handling Instructions Technical Support

ACVR2A/Activin RIIA Protein, Human/Cynomolgus (Biotinylated, HEK293, hFc, Avi) is the recombinant human-derived ACVR2A/Activin RIIA protein, expressed by HEK293, with C-Avi & C-hFc tag.

For research use only. We do not sell to patients.

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Description

ACVR2A/Activin RIIA Protein, Human/Cynomolgus (Biotinylated, HEK293, hFc, Avi) is the recombinant human-derived ACVR2A/Activin RIIA protein, expressed by HEK293, with C-Avi & C-hFc tag.
Background

Activin Receptor Type IIA (ACVR2A) is a transmembrane serine/threonine kinase that forms a heterotetrameric receptor complex with type I receptors upon ligand binding. Functioning as a receptor for activin A, activin B and inhibin A, it initiates SMAD-mediated transcriptional regulation by phosphorylating and activating type I receptors (by similar: mediates GDF6-induced adipogenesis).
Species

Human
Source

HEK293
Tag

C-Avi;C-hFc
Accession

P27037-1 (A20-P135)
Gene ID

92
Molecular Construction
N-term
ACVR2A/Activin RIIA (Ala20-Pro135)
Accession # P27037-1
hF
Avi
C-term
Protein Length

Extracellular Domain
Synonyms
ACTR-IIA; ACTRIIA; ACVR2A; ACVR2
Predicted Molecular Mass
41.2 kDa
Molecular Weight

Approximately 55-70 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.
Glycosylation
Yes
Purity

Greater than 95% as determined by Tris-Bis PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

ACVR2A/Activin RIIA Protein, Human/Cynomolgus (Biotinylated, HEK293, hFc, Avi) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Reconstitution Calculator

  • Dilution Calculator

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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ACVR2A/Activin RIIA Protein, Human/Cynomolgus (Biotinylated, HEK293, hFc, Avi)
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