1. Natural Products
  2. Plants Alkaloids
  3. Zygophyllaceae Pyrrole Alkaloids
  4. Tribulus terrester Linn.
  5. Perlolyrin

Perlolyrin  (Synonyms: Tribulusterine)

Cat. No.: HY-W783671 Purity: 99.81%
Handling Instructions Technical Support

Perlolyrin (Tribulusterine) is an alkaloid that can be isolated from dried fruits of Tribulus terrestris.

For research use only. We do not sell to patients.

Perlolyrin

Perlolyrin Chemical Structure

CAS No. : 29700-20-7

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Based on 1 publication(s) in Google Scholar

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Description

Perlolyrin (Tribulusterine) is an alkaloid that can be isolated from dried fruits of Tribulus terrestris[1].

Cellular Effect
Cell Line Type Value Description References
RAW264.7 IC50
8.7 μM
Compound: 15
Antiinflammatory activity in mouse RAW264.7 cells assessed as reduction in LPS-induced NO production pretreated for 30 mins followed by LPS stimulation for 24 hrs by Griess assay
Antiinflammatory activity in mouse RAW264.7 cells assessed as reduction in LPS-induced NO production pretreated for 30 mins followed by LPS stimulation for 24 hrs by Griess assay
[PMID: 28499733]
Molecular Weight

264.28

Formula

C16H12N2O2

CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

OCC1=CC=C(O1)C2=NC=CC3=C2NC4=C3C=CC=C4

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (378.39 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.7839 mL 18.9193 mL 37.8387 mL
5 mM 0.7568 mL 3.7839 mL 7.5677 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.7839 mL 18.9193 mL 37.8387 mL 94.5966 mL
5 mM 0.7568 mL 3.7839 mL 7.5677 mL 18.9193 mL
10 mM 0.3784 mL 1.8919 mL 3.7839 mL 9.4597 mL
15 mM 0.2523 mL 1.2613 mL 2.5226 mL 6.3064 mL
20 mM 0.1892 mL 0.9460 mL 1.8919 mL 4.7298 mL
25 mM 0.1514 mL 0.7568 mL 1.5135 mL 3.7839 mL
30 mM 0.1261 mL 0.6306 mL 1.2613 mL 3.1532 mL
40 mM 0.0946 mL 0.4730 mL 0.9460 mL 2.3649 mL
50 mM 0.0757 mL 0.3784 mL 0.7568 mL 1.8919 mL
60 mM 0.0631 mL 0.3153 mL 0.6306 mL 1.5766 mL
80 mM 0.0473 mL 0.2365 mL 0.4730 mL 1.1825 mL
100 mM 0.0378 mL 0.1892 mL 0.3784 mL 0.9460 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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