2. GPCR/G Protein Immunology/Inflammation
  3. CXCR
  4. NI-0701

NI-0701 is a humanized antibody expressed in CHO cells that targets CCL5/RANTES. NI-0701 has a huIgG2 heavy chain and a huλ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for NI-0701 can be referenced as Human IgG2 kappa, Isotype Control (HY-P99002).

For research use only. We do not sell to patients.

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Based on 1 publication(s) in Google Scholar

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Description

NI-0701 is a humanized antibody expressed in CHO cells that targets CCL5/RANTES. NI-0701 has a huIgG2 heavy chain and a huλ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for NI-0701 can be referenced as Human IgG2 kappa, Isotype Control (HY-P99002).

Isotype

Human IgG2 kappa
Recommend Isotype Controls
IC50 & Target

CCL5/RANTES
Clinical Trial
Gene ID

6352  [NCBI]

Accession
Application

ELISA, FACS, Functional assay
Conjugated

Unconjugated
Reconsititution

The product can be reconstituted/diluted with sterile PBS or saline.
Molecular Weight

145.5 kDa

Appearance

Liquid

Color

Colorless to light yellow

Shipping

Shipping with dry ice.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
  • Immobilized RANTES/CCL5 Protein, Human can bind NI-0701. The EC50 for this effect is 47.52 ng/mL.
Purity & Documentation
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NI-0701 Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NI-0701NI0701NI 0701CXCRCXC chemokine receptorsC-X-C motif chemokine receptorsHuman AntibodyCCL5/RANTES AntibodyInhibitorinhibitorinhibit

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NI-0701
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HY-P990638
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