2. Academic Validation
  3. A phospholipid immunomodulator from Akkermansia muciniphila

A phospholipid immunomodulator from Akkermansia muciniphila

  • Cell Host Microbe. 2022 Sep 14;30(9):1191-1193. doi: 10.1016/j.chom.2022.08.014.
Subho Ghosh 1,  Sridhar Mani 2
Affiliations

Affiliations

  • 1 Departments of Medicine, Molecular Pharmacology and Genetics, Albert Einstein College of Medicine, Bronx, NY, USA. Electronic address: subho.ghosh@einsteinmed.edu.
  • 2 Departments of Medicine, Molecular Pharmacology and Genetics, Albert Einstein College of Medicine, Bronx, NY, USA. Electronic address: sridhar.mani@einsteinmed.edu.
PMID: 36108608 DOI: 10.1016/j.chom.2022.08.014
Abstract

A recent paper in Nature (Bae et al., 2022) reports the discovery of a phosphatidylethanolamine from Akkermansia muciniphila that mediates the immunomodulatory function of the bacterium via regulation of the Toll-like Receptor 2 (TLR2) or the TLR2-TLR1 signaling complex in immune cells.

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