1. Academic Validation
  2. Diagnosis of Peritoneal Tuberculosis from Primary Peritoneal Cancer

Diagnosis of Peritoneal Tuberculosis from Primary Peritoneal Cancer

  • Int J Environ Res Public Health. 2021 Oct 3;18(19):10407. doi: 10.3390/ijerph181910407.
I-Hui Chen 1 2 Pao-Ling Torng 1 2 Chia-Yi Lee 1 2 3 Kuang-Han Lee 1 4 Heng-Cheng Hsu 1 2 3 Wen-Fang Cheng 2 3 5
Affiliations

Affiliations

  • 1 Department of Obstetrics and Gynecology, National Taiwan University Hospital Hsin-Chu Branch, Hsin-Chu 300, Taiwan.
  • 2 Department of Obstetrics and Gynecology, National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei 100, Taiwan.
  • 3 Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei 100, Taiwan.
  • 4 Department of Obstetrics and Gynecology, Chu-Tung Branch, Hsin-Chu 310, Taiwan.
  • 5 Graduate Institute of Oncology, College of Medicine, National Taiwan University, Taipei 100, Taiwan.
Abstract

Peritoneal tuberculosis (PTB) is an uncommon extrapulmonary Infection mimickng primary peritoneal Cancer (PPC). We retrospectively included 23 women with PTB and 47 women with PPC treated in a medical center to study the clinical and radiological features that differentiate PTB from PPC. Body temperature above 38 °C was a unique feature of PTB (34.7% versus 0%, p < 0.001). Body Mass Index (BMI) was lower (21.9 ± 3.7 versus 25.2 ± 4.1, p = 0.003), white blood cell (WBC) count was lower (5179.6 ± 1502.2 versus 7716.2 ± 2741.8, p < 0.001), and CA-125 level was lower (508.0 ± 266.1 versus 2130.1 ± 2367.2 U/mL, p < 0.001) in PTB compared with PPC. Imaging detected more pulmonary infiltration and consolidation (52.2% versus 6.4%, p < 0.001), and less omental/mesentery changes (52% versus 83%, p < 0.001) in PTB compared with PPC. The operated patients received earlier treatment compared to patients without operation (7.9 ± 5.3 days versus 17.2 ± 11.0 days, p = 0.010). In conclusion, fever above 38 °C, lower BMI, lower WBC count, less elevated CA-125 level, and imaging of less omental involvement were features of PTB differentiated from PPC.

Keywords

peritoneal neoplasms; radiography; symptom assessment; tuberculous peritonitis.

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