2. Academic Validation
  3. Cytotoxic and novel compounds from Solanum indicum

Cytotoxic and novel compounds from Solanum indicum

  • J Nat Prod. 2001 Sep;64(9):1232-3. doi: 10.1021/np010186v.
W J Syu 1,  M J Don,  G H Lee,  C M Sun
Affiliations

Affiliation

  • 1 Institute of Microbiology and Immunology, National Yang-Ming University, Taipei 112, Taiwan.
PMID: 11575964 DOI: 10.1021/np010186v
Abstract

Solavetivone (1), cytotoxic to OVCAR-3 cells with an IC(50) value of 0.1 mM, has been isolated from Solanum indicum. In addition, a novel solafuranone (2) and three known compounds, scopoletin, N-(p-trans-coumaroyl)tyramine, and N-trans-feruloyltyramine, were isolated for the first time from this plant. The structures of the above compounds were established by means of spectroscopic and X-ray analyses.

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