1. Academic Validation
  2. Haematocin, a new antifungal diketopiperazine produced by Nectria haematococca Berk. et Br. (880701a-1) causing nectria blight disease on ornamental plants

Haematocin, a new antifungal diketopiperazine produced by Nectria haematococca Berk. et Br. (880701a-1) causing nectria blight disease on ornamental plants

  • J Antibiot (Tokyo). 2000 Jan;53(1):45-9. doi: 10.7164/antibiotics.53.45.
Y Suzuki 1 H Takahashi Y Esumi T Arie T Morita H Koshino J Uzawa M Uramoto I Yamaguchi
Affiliations

Affiliation

  • 1 The Institute of Physical and Chemical Research (RIKEN), Wako-shi, Saitama, Japan.
Abstract

A new Antifungal diketopiperazine named haematocin was isolated from the culture broth of Nectria haematococca Berk. et Br. (880701a-1) causing blight disease on ornamental Plants, Phalaenopsis spp. and Doritanopsis spp. Its structure was established by spectroscopic methods. Haematocin inhibited the germ-tube elongation and spore-germination of Pyricularia oryzae at the ED50 values of 30 microg/ml and 160 microg/ml, respectively.

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