Indole-2-carbaldehyde

Name: Indole-2-carbaldehyde
Brand: MedChemExpress
SKU: HY-W015650
Rating: 4.5 (1 reviews)

Cat. No.: HY-W015650 Purity: 99.34%: Data Sheet
SDS

COA
Handling Instructions
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Indole-2-carbaldehyde is an indole derivative that can be used to reduce or remove localized fat deposits and/or tighten loose skin and soft tissues. Indole-2-carbaldehyde can be isolated from the fermentation broth of the coral symbiotic actinomycete Pseudonocardia sp. SCSIO 11457 and is used in cosmetic applications or pharmaceutical production.

For research use only. We do not sell to patients.

Indole-2-carbaldehyde Chemical Structure

CAS No. : 19005-93-7

Size	Stock	Quantity
Free Sample (0.1 - 0.5 mg)	Apply Now
1 g	In-stock	Estimated Time of Arrival: December 31
5 g	In-stock	Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
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Description

In Vitro

Indole-2-carbaldehyde has no significant antibacterial activity against pathogenic bacteria and no cytotoxic activity against human cancer cell lines^[1].
Indole-2-carbaldehyde (compound 2) exhibits a higher killing rate against adipocytes and is more specific to adipocytes than to neural cells, dermal cells, muscle cells, and endothelial cells^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

145.16

Formula

C₉H₇NO

CAS No.

19005-93-7

Appearance

Solid

Color

Off-white to light brown

SMILES

O=CC1=CC2=C(N1)C=CC=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (688.90 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	6.8889 mL	34.4447 mL	68.8895 mL
5 mM	1.3778 mL	6.8889 mL	13.7779 mL
10 mM	0.6889 mL	3.4445 mL	6.8889 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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In Vivo Dissolution Calculator

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Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.81%

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Data Sheet (273 KB) SDS (393 KB)

COA (250 KB)

Handling Instructions (2659 KB)

References

[1]. Fang Z, et al. A new uridine derivative and a new indole derivative from the coral-associated actinomycete Pseudonocardia sp. SCSIO 11457. Nat Prod Res. 2021 Jan;35(2):188-194. [Content Brief]

[2]. Use of indole compounds for fat reduction and skin and soft tissue tightening. World Intellectual Property Organization, WO2014143125 A1 2014-09-18.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	6.8889 mL	34.4447 mL	68.8895 mL	172.2237 mL
	5 mM	1.3778 mL	6.8889 mL	13.7779 mL	34.4447 mL
	10 mM	0.6889 mL	3.4445 mL	6.8889 mL	17.2224 mL
	15 mM	0.4593 mL	2.2963 mL	4.5926 mL	11.4816 mL
	20 mM	0.3444 mL	1.7222 mL	3.4445 mL	8.6112 mL
	25 mM	0.2756 mL	1.3778 mL	2.7556 mL	6.8889 mL
	30 mM	0.2296 mL	1.1482 mL	2.2963 mL	5.7408 mL
	40 mM	0.1722 mL	0.8611 mL	1.7222 mL	4.3056 mL
	50 mM	0.1378 mL	0.6889 mL	1.3778 mL	3.4445 mL
	60 mM	0.1148 mL	0.5741 mL	1.1482 mL	2.8704 mL
	80 mM	0.0861 mL	0.4306 mL	0.8611 mL	2.1528 mL
	100 mM	0.0689 mL	0.3444 mL	0.6889 mL	1.7222 mL