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  6. Gentisin

Gentisin is a natural compound. Gentisin can be extracted from Gentianae radix (Gentianaceae). Gentisin has mutagenic activity. Gentisin can be used in vascular smooth muscle research.

For research use only. We do not sell to patients.

Gentisin

Gentisin Chemical Structure

CAS No. : 437-50-3

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Based on 1 publication(s) in Google Scholar

Gentisin Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

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Description

Gentisin is a natural compound. Gentisin can be extracted from Gentianae radix (Gentianaceae). Gentisin has mutagenic activity. Gentisin can be used in vascular smooth muscle research[1][2].

Cellular Effect
Cell Line Type Value Description References
A549 IC50
103.76 μM
Compound: 6
Cytotoxicity against Taxol-resistant human A549 cells measured after 48 hrs by MTT assay
Cytotoxicity against Taxol-resistant human A549 cells measured after 48 hrs by MTT assay
[PMID: 28065566]
NCI/ADR-RES IC50
31.82 μM
Compound: 6
Cytotoxicity against human MCF7/ADR cells measured after 48 hrs by MTT assay
Cytotoxicity against human MCF7/ADR cells measured after 48 hrs by MTT assay
[PMID: 28065566]
SMMC-7721 IC50
87.44 μM
Compound: 6
Cytotoxicity against Taxol-resistant human SMMC7721 cells measured after 48 hrs by MTT assay
Cytotoxicity against Taxol-resistant human SMMC7721 cells measured after 48 hrs by MTT assay
[PMID: 28065566]
In Vitro

Gentisin (1-30 µM; 48 h) inhibits PDGF-induced vascular smooth muscle cell proliferation in a concentration-dependent manner with an IC50 of 7.84 µM[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Gentisin Related Antibodies
Molecular Weight

258.23

Formula

C14H10O5
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C1C2=C(OC3=C1C=C(O)C=C3)C=C(OC)C=C2O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Purity & Documentation

Purity: 98.88%

SDS (252 KB)

COA (247 KB) LCMS (87 KB)

Handling Instructions (2659 KB)
References
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Gentisin Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Gentisin437-50-3OthersInhibitorinhibitorinhibit

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