2. Gene
  3. Gata3 - GATA binding protein 3 Gene

Gata3 - GATA binding protein 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 85471 | Gene type: protein coding

About Gata3

Summary

Enables DNA-binding transcription factor activity and sequence-specific DNA binding activity. Involved in several processes, including cochlea development; response to gamma radiation; and type IV hypersensitivity. Located in nucleus. Biomarker of asthma. Human ortholog(s) of this gene implicated in hypoparathyroidism; hypoparathyroidism-deafness-renal disease syndrome; nephrosis; and sensorineural hearing loss. Orthologous to human GATA3 (GATA binding protein 3). [provided by Alliance of Genome Resources, Apr 2022]

Gata3 Products(1)

mRNA Protein Name
NM_133293.2 NP_579827.1 trans-acting T-cell-specific transcription factor GATA-3
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables DNA-binding transcription factor activity IMP
IMP: Inferred from mutant phenotype
9125153 RGD
enables histone methyltransferase binding IPI
IPI: Inferred from physical interaction
34694864 RGD
enables sequence-specific DNA binding IMP
IMP: Inferred from mutant phenotype
9125153 RGD
Biological Process GO Annotation Evidence Reference Source
involved in cochlea development IEP
IEP: Inferred from expression pattern
20006695 RGD
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
9125153 RGD
involved in response to ethanol IEP
IEP: Inferred from expression pattern
19428696 RGD
involved in response to gamma radiation IEP
IEP: Inferred from expression pattern
19084914 RGD
involved in response to xenobiotic stimulus IEP
IEP: Inferred from expression pattern
19428696 RGD
involved in type IV hypersensitivity IEP
IEP: Inferred from expression pattern
16336837 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

trans-acting T-cell-specific transcription factor GATA-3

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-138113 Pyrrothiogatain Inhibitor 98.61% Unkown
HY-N0407 Picroside I Inhibitor 99.55% Unkown
HY-RS05291 GATA3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS17910 Gata3 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24379 Gata3 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Gata3 NCBI NCBI:2625