Cdc5l - cell division cycle 5-like Gene

Rattus norvegicus

Gene ID: 85434 | Gene type: protein coding

About Cdc5l

Summary

Enables enzyme binding activity; leucine zipper domain binding activity; and transcription corepressor binding activity. Involved in several processes, including cellular response to growth factor stimulus; cellular response to prolactin; and cellular response to wortmannin. Located in nuclear speck and perinuclear region of cytoplasm. Part of protein-DNA complex. Human ortholog(s) of this gene implicated in osteosarcoma. Orthologous to human CDC5L (cell division cycle 5 like). [provided by Alliance of Genome Resources, Apr 2022]

Cdc5l Products(1)

mRNA	Protein	Name
NM_053527.2	NP_445979.1	cell division cycle 5-like protein

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables leucine zipper domain binding	IPI IPI: Inferred from physical interaction	11884640	RGD
enables protein binding	IPI IPI: Inferred from physical interaction	16352598	RGD
enables protein kinase binding	IPI IPI: Inferred from physical interaction	11884640	RGD
enables protein phosphatase 1 binding	IPI IPI: Inferred from physical interaction	10827081	RGD
enables transcription corepressor binding	IPI IPI: Inferred from physical interaction	20629186	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in cellular response to fibroblast growth factor stimulus	IEP IEP: Inferred from expression pattern	11694351	RGD
involved in cellular response to interleukin-2	IEP IEP: Inferred from expression pattern	11694351	RGD
involved in cellular response to nerve growth factor stimulus	IDA IDA: Inferred from direct assay	20629186	RGD
involved in cellular response to prolactin	IEP IEP: Inferred from expression pattern	9296381	RGD
involved in cellular response to wortmannin	IDA IDA: Inferred from direct assay	20629186	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in nuclear speck	IDA IDA: Inferred from direct assay	11884640	RGD
located in perinuclear region of cytoplasm	IDA IDA: Inferred from direct assay	11694351	RGD
part of protein-DNA complex	IDA IDA: Inferred from direct assay	11694351	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

cell division cycle 5-like protein

CDC5 cell division cycle 5-like	cdc5-like protein
cell division cycle 5-related protein	pombe Cdc5-related protein

Related Agents

Pre-clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-15339	CVT-313	Inhibitor	99.90%	Unkown
HY-RS02307	CDC5L Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS21510	Cdc5l Mouse Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS28028	Cdc5l Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Cdc5l	NCBI	NCBI:988

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