2. Gene
  3. Pola1 - DNA polymerase alpha 1, catalytic subunit Gene

Pola1 - DNA polymerase alpha 1, catalytic subunit Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 85241 | Gene type: protein coding

About Pola1

Summary

Enables DNA-directed DNA Polymerase activity; double-stranded DNA binding activity; and nucleotide binding activity. Involved in DNA biosynthetic process and DNA replication. Part of alpha DNA polymerase:primase complex. Human ortholog(s) of this gene implicated in Van Esch-O'Driscoll syndrome and X-linked reticulate pigmentary disorder. Orthologous to human POLA1 (DNA Polymerase alpha 1, catalytic subunit). [provided by Alliance of Genome Resources, Apr 2022]

Pola1 Products(1)

mRNA Protein Name
NM_053479.1 NP_445931.1 DNA polymerase alpha catalytic subunit
Protein Preferred Names Protein Names

DNA polymerase alpha catalytic subunit

DNA polymerase alpha catalytic subunit p180

DNA polymerase alpha subunit I

polymerase (DNA directed), alpha 1, catalytic subunit

polymerase (DNA) alpha 1, catalytic subunit

Related Agents

Pre-clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-147812 POLA1 inhibitor 1 Inhibitor 98.85% Unkown
HY-143411 GEM144 / Unkown
HY-143412 MIR002 ≥99.0% Unkown
HY-RS10816 POLA1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS17305 Pola1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS23760 Pola1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pola1 NCBI NCBI:5422