2. Gene
  3. Mlycd - malonyl-CoA decarboxylase Gene

Mlycd - malonyl-CoA decarboxylase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Mcd

Gene ID: 85239 | Gene type: protein coding

About Mlycd

Summary

Enables malonyl-CoA decarboxylase activity. Involved in several processes, including acetyl-CoA biosynthetic process; fatty acid metabolic process; and response to ischemia. Located in cytosol; mitochondrial matrix; and peroxisomal matrix. Human ortholog(s) of this gene implicated in cardiomyopathy. Orthologous to human MLYCD (malonyl-CoA decarboxylase). [provided by Alliance of Genome Resources, Apr 2022]

Mlycd Products(1)

mRNA Protein Name
NM_053477.2 NP_445929.2 malonyl-CoA decarboxylase, mitochondrial
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables malonyl-CoA decarboxylase activity IDA
IDA: Inferred from direct assay
12065578 RGD
Biological Process GO Annotation Evidence Reference Source
involved in acetyl-CoA biosynthetic process IDA
IDA: Inferred from direct assay
17316539 RGD
involved in fatty acid biosynthetic process IMP
IMP: Inferred from mutant phenotype
15105298 RGD
involved in fatty acid oxidation IDA
IDA: Inferred from direct assay
17316539 RGD
involved in regulation of fatty acid beta-oxidation IDA
IDA: Inferred from direct assay
10516138 RGD
involved in regulation of fatty acid oxidation IMP
IMP: Inferred from mutant phenotype
15105298 RGD
involved in regulation of glucose metabolic process IMP
IMP: Inferred from mutant phenotype
15105298 RGD
involved in response to ischemia IMP
IMP: Inferred from mutant phenotype
15105298 RGD
involved in response to nutrient IEP
IEP: Inferred from expression pattern
26394137 RGD
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
10455107 RGD
located in mitochondrial matrix IDA
IDA: Inferred from direct assay
16298369 RGD
located in peroxisomal matrix IDA
IDA: Inferred from direct assay
16298369 RGD
located in peroxisome IDA
IDA: Inferred from direct assay
10455107 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

malonyl-CoA decarboxylase, mitochondrial

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS08506 MLYCD Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21650 Mlycd Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28168 Mlycd Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mlycd NCBI NCBI:23417