2. Gene
  3. NDST2 - N-deacetylase and N-sulfotransferase 2 Gene

NDST2 - N-deacetylase and N-sulfotransferase 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as NST2; HSST2; N-HSST 2

Gene ID: 8509 | Gene type: protein coding

About NDST2

Cytogenetic location: 10q22.2 Genomic coordinates (GRCh38): 10:73,801,916-73,811,820 (from NCBI)

This gene has 6 transcripts (splice variants), 207 orthologues and 10 paralogues. Ubiquitous expression in spleen (RPKM 13.3), bone marrow (RPKM 9.9) and 25 other tissues.

Summary

This gene encodes a member of the N-deacetylase/N-sulfotransferase subfamily of the sulfotransferase 1 proteins. The encoded enzyme has dual functions in processing glucosamine and heparin Polymers, including N-deacetylation and N-sulfation. The encoded protein may be localized to the Golgi. [provided by RefSeq, Feb 2009]

NDST2 Products(2)

mRNA Protein Name
NM_001330107.2 NP_001317036.1 bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 isoform 2
NM_003635.4 NP_003626.1 bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 isoform 1

NDST2 Protein Structure

HSNSD

HSNSD: heparan sulfate-N-deacetylase (1 - 391)

Sulfotransfer_1

Sulfotransfer_1: Sulfotransferase domain (481 - 729)

  • 0
  • 200
  • 400
  • 600
  • 760 a.a.
Protein Preferred Names Protein Names

bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2

N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS09119 NDST2 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta NDST2 VGNC VGNC:106079
Mus musculus NDST2 MGD MGI:97040
Canis familiaris NDST2 VGNC VGNC:51905
Rattus norvegicus NDST2 RGD RGD:1304700