2. Gene
  3. Asah1 - N-acylsphingosine amidohydrolase 1 Gene

Asah1 - N-acylsphingosine amidohydrolase 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Asah

Gene ID: 84431 | Gene type: protein coding

About Asah1

Summary

Predicted to enable N-acylsphingosine amidohydrolase activity; nuclear receptor binding activity; and transcription corepressor activity. Involved in lung development and response to organic substance. Predicted to be located in extracellular space; lysosome; and nucleus. Human ortholog(s) of this gene implicated in Farber lipogranulomatosis; sphingolipidosis; and spinal muscular atrophy with progressive myoclonic epilepsy. Orthologous to human ASAH1 (N-acylsphingosine amidohydrolase 1). [provided by Alliance of Genome Resources, Apr 2022]

Asah1 Products(1)

mRNA Protein Name
NM_053407.3 NP_445859.2 acid ceramidase precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in lung development IDA
IDA: Inferred from direct assay
9160843 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

acid ceramidase

AC

ACDase

N-acylethanolamine hydrolase ASAH1

N-acylsphingosine amidohydrolase (acid ceramidase) 1

acid CDase

acylsphingosine deacylase

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-141866 Acid Ceramidase-IN-1 99.36% Unkown
HY-158783 SACLAC 99.70% Unkown
HY-RS01053 ASAH1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18163 Asah1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24637 Asah1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Asah1 NCBI NCBI:427