2. Gene
  3. Clcn3 - chloride voltage-gated channel 3 Gene

Clcn3 - chloride voltage-gated channel 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as ClC-3

Gene ID: 84360 | Gene type: protein coding

About Clcn3

Summary

Enables voltage-gated Chloride Channel activity. Involved in chloride transport. Located in apical plasma membrane; inhibitory synapse; and synaptic vesicle. Is integral component of membrane. Is active in glutamatergic synapse. Is integral component of postsynaptic membrane. Orthologous to human CLCN3 (chloride voltage-gated channel 3). [provided by Alliance of Genome Resources, Apr 2022]

Clcn3 Products(2)

mRNA Protein Name
NM_001413712.1 NP_001400641.1 H(+)/Cl(-) exchange transporter 3 isoform 2
NM_053363.3 NP_445815.2 H(+)/Cl(-) exchange transporter 3 isoform 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables chloride channel activity IDA
IDA: Inferred from direct assay
10915634 RGD
enables monoatomic ion channel activity IDA
IDA: Inferred from direct assay
10915634 RGD
enables voltage-gated chloride channel activity IDA
IDA: Inferred from direct assay
10915634 RGD
enables voltage-gated monoatomic ion channel activity IDA
IDA: Inferred from direct assay
10915634 RGD
Biological Process GO Annotation Evidence Reference Source
involved in chloride transport IDA
IDA: Inferred from direct assay
10915634 RGD
involved in monoatomic ion transport IDA
IDA: Inferred from direct assay
10915634 RGD
Cellular Component GO Annotation Evidence Reference Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
12475763 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
17046694 RGD
located in inhibitory synapse IDA
IDA: Inferred from direct assay
21378974 RGD
located in plasma membrane IDA
IDA: Inferred from direct assay
10915634 RGD
is active in postsynaptic membrane IDA
IDA: Inferred from direct assay
17046694 RGD
located in synapse IDA
IDA: Inferred from direct assay
11182090 RGD
located in synaptic vesicle IDA
IDA: Inferred from direct assay
21378974 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

H(+)/Cl(-) exchange transporter 3

chloride channel 3

chloride channel protein 3

chloride channel, voltage-sensitive 3

chloride transporter ClC-3

protein kinase C-regulated chloride channel

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02755 CLCN3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS21531 Clcn3 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS28049 Clcn3 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Clcn3 NCBI NCBI:1182