2. Gene
  3. Vdac1 - voltage-dependent anion channel 1 Gene

Vdac1 - voltage-dependent anion channel 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 83529 | Gene type: protein coding

About Vdac1

Summary

Enables voltage-gated anion channel activity. Involved in mitochondrial calcium ion transmembrane transport. Located in mitochondrial outer membrane and synaptic vesicle. Part of protein-containing complex. Used to study visual epilepsy. Human ortholog(s) of this gene implicated in prostate Cancer. Orthologous to human VDAC1 (voltage dependent anion channel 1). [provided by Alliance of Genome Resources, Apr 2022]

Vdac1 Products(1)

mRNA Protein Name
NM_031353.2 NP_112643.1 voltage-dependent anion-selective channel protein 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables monoatomic anion channel activity IDA
IDA: Inferred from direct assay
12438411 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
9843949 RGD
enables protein-containing complex binding IDA
IDA: Inferred from direct assay
9459579 RGD
enables voltage-gated channel activity IDA
IDA: Inferred from direct assay
450112 RGD
enables voltage-gated monoatomic anion channel activity IDA
IDA: Inferred from direct assay
12438411 RGD
Biological Process GO Annotation Evidence Reference Source
involved in calcium import into the mitochondrion IMP
IMP: Inferred from mutant phenotype
11485562 RGD
involved in mitochondrial calcium ion transmembrane transport IDA
IDA: Inferred from direct assay
12438411 RGD
Cellular Component GO Annotation Evidence Reference Source
located in mitochondrial outer membrane IDA
IDA: Inferred from direct assay
12438411 RGD
is active in postsynaptic density membrane IDA
IDA: Inferred from direct assay
10208569 RGD
is active in presynaptic active zone membrane EXP
EXP: Inferred from Experiment
19187093 RGD
is active in presynaptic active zone membrane IDA
IDA: Inferred from direct assay
19187093 RGD
part of protein-containing complex IDA
IDA: Inferred from direct assay
9459579 RGD
located in synaptic vesicle IDA
IDA: Inferred from direct assay
19187093 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

voltage-dependent anion-selective channel protein 1

VDAC-1

outer mitochondrial membrane protein porin 1

rVDAC1

Related Agents

Pre-clinical Phase
Bioactive Molecules (12)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-D0086 DIDS sodium salt Inhibitor 99.13% Unkown
HY-129122 VBIT-4 Inhibitor 99.46% Unkown
HY-108937 NSC 15364 Inhibitor 99.67% Unkown
HY-135885 VBIT-12 Inhibitor 98.87% Unkown
HY-111217 AKOS-22 Inhibitor 99.23% Unkown
HY-RS15629 VDAC1 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-121693 DIDS Inhibitor / Unkown
HY-135571 VBIT-3 Inhibitor / Unkown
HY-161027 DHP-B Inducer / Unkown
HY-176745 SW016789 Inducer / Unkown
HY-RS16872 Vdac1 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS23313 Vdac1 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Vdac1 NCBI NCBI:7416