N4bp1 - NEDD4 binding protein 1 Gene

Mus musculus

Gene ID: 80750 | Gene type: protein coding

About N4bp1

Summary

Predicted to enable mRNA binding activity; ribonuclease activity; and ubiquitin binding activity. Involved in cellular response to UV; negative regulation of macromolecule metabolic process; and regulation of innate immune response. Located in PML body; cytosol; and nucleolus. Orthologous to human N4BP1 (NEDD4 binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]

N4bp1 Products(1)

mRNA	Protein	Name
NM_030563.2	NP_085040.2	NEDD4-binding protein 1

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	11717310	MGI

Biological Process GO Annotation	Evidence	Reference	Source
involved in cellular response to UV	IMP IMP: Inferred from mutant phenotype	17592138	MGI
involved in negative regulation of cytokine production	IMP IMP: Inferred from mutant phenotype	32971525	MGI
involved in negative regulation of proteasomal ubiquitin-dependent protein catabolic process	IDA IDA: Inferred from direct assay	17592138	MGI
involved in negative regulation of protein ubiquitination	IDA IDA: Inferred from direct assay	17592138	MGI
involved in regulation of innate immune response	IDA IDA: Inferred from direct assay	32971525	MGI

Cellular Component GO Annotation	Evidence	Reference	Source
located in PML body	IDA IDA: Inferred from direct assay	20233849	MGI
located in cytosol	IDA IDA: Inferred from direct assay	32971525	MGI
located in nucleolus	IDA IDA: Inferred from direct assay	20233849	MGI
located in nucleus	IDA IDA: Inferred from direct assay	11717310	MGI

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

NEDD4-binding protein 1

N4bp1 Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P83541	N4BP1 Antibody (YA3286)	WB, IP	Human

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08979	N4BP1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	N4bp1	NCBI	NCBI:9683

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