2. Gene
  3. Cln6 - ceroid-lipofuscinosis, neuronal 6 Gene

Cln6 - ceroid-lipofuscinosis, neuronal 6 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as nclf; D9Bwg1455e; 1810065L06Rik

Gene ID: 76524 | Gene type: protein coding

About Cln6

Summary

Predicted to enable lysophosphatidic acid binding activity; protein homodimerization activity; and sulfatide binding activity. Acts upstream of or within several processes, including locomotion involved in locomotory behavior; lysosome organization; and visual perception. Predicted to be located in several cellular components, including early endosome; endoplasmic reticulum lumen; and membrane raft. Predicted to be active in endoplasmic reticulum and membrane. Is expressed in several structures, including central nervous system and retina. Used to study neuronal ceroid lipofuscinosis 6. Human ortholog(s) of this gene implicated in neuronal ceroid lipofuscinosis; neuronal ceroid lipofuscinosis 4A; and neuronal ceroid lipofuscinosis 6. Orthologous to human CLN6 (CLN6 transmembrane ER protein). [provided by Alliance of Genome Resources, Apr 2022]

Cln6 Products(2)

mRNA Protein Name
NM_001033175.3 NP_001028347.1 ceroid-lipofuscinosis neuronal protein 6
NM_001033175.3 NP_001028347.1 ceroid-lipofuscinosis neuronal protein 6
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within locomotion involved in locomotory behavior IMP
IMP: Inferred from mutant phenotype
9600738 MGI
acts upstream of or within lysosome organization IMP
IMP: Inferred from mutant phenotype
9600738 MGI
acts upstream of or within macromolecule catabolic process IMP
IMP: Inferred from mutant phenotype
15647513 MGI
acts upstream of or within visual perception IMP
IMP: Inferred from mutant phenotype
9600738 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ceroid-lipofuscinosis neuronal protein 6

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS02824 CLN6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22123 Cln6 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28645 Cln6 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cln6 NCBI NCBI:54982