2. Gene
  3. Rd3 - retinal degeneration 3 Gene

Rd3 - retinal degeneration 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as rd3; rd-3; 3322402L07Rik

Gene ID: 74023 | Gene type: protein coding

About Rd3

Summary

Involved in negative regulation of Guanylate Cyclase activity and visual perception. Acts upstream of or within retina development in camera-type eye. Located in nucleus; photoreceptor inner segment; and photoreceptor outer segment. Is expressed in brain and sensory organ. Used to study Leber congenital amaurosis 12. Human ortholog(s) of this gene implicated in Leber congenital amaurosis; Leber congenital amaurosis 12; and retinal degeneration. Orthologous to human RD3 (RD3 regulator of GUCY2D). [provided by Alliance of Genome Resources, Apr 2022]

Rd3 Products(3)

mRNA Protein Name
NM_001177900.2 NP_001171371.2 protein RD3 isoform 2
NM_001303132.1 NP_001290061.1 protein RD3 isoform 2
NM_023727.4 NP_076216.3 protein RD3 isoform 1
Protein Preferred Names Protein Names

protein RD3

retinal degeneration protein 3

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-100285 RD3-0028 Inhibitor / Unkown
HY-RS11796 RD3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS11797 RD3L Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS19868 Rd3 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26367 Rd3 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rd3 NCBI NCBI:343035