2. Gene
  3. Flrt3 - fibronectin leucine rich transmembrane protein 3 Gene

Flrt3 - fibronectin leucine rich transmembrane protein 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as mKIAA1469; 5530600M07Rik; C430047I10Rik

Gene ID: 71436 | Gene type: protein coding

About Flrt3

Summary

Enables chemorepellent activity and Fibroblast Growth Factor receptor binding activity. Involved in several processes, including Fibroblast Growth Factor receptor signaling pathway; proepicardium cell migration involved in pericardium morphogenesis; and synapse organization. Acts upstream of or within positive regulation of synapse assembly. Located in several cellular components, including axonal growth cone; cell-cell junction; and glutamatergic synapse. Is integral component of postsynaptic membrane. Colocalizes with focal adhesion. Is expressed in several structures, including alimentary system; brain; embryo ectoderm; embryo mesenchyme; and eye. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 21 with or without anosmia. Orthologous to human FLRT3 (fibronectin leucine rich transmembrane protein 3). [provided by Alliance of Genome Resources, Apr 2022]

Flrt3 Products(2)

mRNA Protein Name
NM_001172160.1 NP_001165631.1 leucine-rich repeat transmembrane protein FLRT3 precursor
NM_178382.4 NP_848469.1 leucine-rich repeat transmembrane protein FLRT3 precursor
Protein Preferred Names Protein Names

leucine-rich repeat transmembrane protein FLRT3

Flrt3 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
Flrt3 Q8BGT1 App Mus musculus P12023
Anti Bait CoIP
26960425
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04986 FLRT3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS20409 Flrt3 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS26918 Flrt3 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Flrt3 NCBI NCBI:23767