2. Gene
  3. Lman1 - lectin, mannose-binding, 1 Gene

Lman1 - lectin, mannose-binding, 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as P58; MR60; gp58; F5F8D; MCFD1; ERGIC53; C730041J05; 2610020P13Rik

Gene ID: 70361 | Gene type: protein coding

About Lman1

Summary

Predicted to enable identical protein binding activity and mannose binding activity. Acts upstream of or within endoplasmic reticulum organization. Located in several cellular components, including COPII-coated ER to Golgi transport vesicle; endoplasmic reticulum-Golgi intermediate compartment; and sarcomere. Is expressed in pancreas epithelium. Human ortholog(s) of this gene implicated in factor V deficiency and factor XIII deficiency. Orthologous to human LMAN1 (lectin, mannose binding 1). [provided by Alliance of Genome Resources, Apr 2022]

Lman1 Products(2)

mRNA Protein Name
NM_001172062.1 NP_001165533.1 protein ERGIC-53 precursor
NM_027400.3 NP_081676.1 protein ERGIC-53 precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within endoplasmic reticulum organization IMP
IMP: Inferred from mutant phenotype
21795745 MGI
Cellular Component GO Annotation Evidence Reference Source
located in COPII-coated ER to Golgi transport vesicle IDA
IDA: Inferred from direct assay
19966784 MGI
located in Golgi apparatus IDA
IDA: Inferred from direct assay
10787428 MGI
located in endoplasmic reticulum-Golgi intermediate compartment IDA
IDA: Inferred from direct assay
14645249 MGI
located in sarcomere IDA
IDA: Inferred from direct assay
14728599 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein ERGIC-53

ER-Golgi intermediate compartment 53 kDa protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07703 LMAN1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22612 Lman1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29127 Lman1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Lman1 NCBI NCBI:3998