Ndufc2 - NADH:ubiquinone oxidoreductase subunit C2 Gene

Mus musculus

Also known as G1; 1810004I06Rik; 2010300P09Rik

Gene ID: 68197 | Gene type: protein coding

About Ndufc2

Summary

Predicted to enable NADH dehydrogenase (ubiquinone) activity. Predicted to be involved in several processes, including mitochondrial respiratory chain complex I assembly; negative regulation of NIK/NF-kappaB signaling; and positive regulation of ATP biosynthetic process. Located in mitochondrial inner membrane. Is expressed in several structures, including gut; male reproductive gland or organ; and nervous system. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency. Orthologous to several human genes including NDUFC2 (NADH:ubiquinone oxidoreductase subunit C2). [provided by Alliance of Genome Resources, Apr 2022]

Ndufc2 Products(1)

mRNA	Protein	Name
NM_024220.2	NP_077182.1	NADH dehydrogenase [ubiquinone] 1 subunit C2

Protein Preferred Names

Protein Names

NADH dehydrogenase [ubiquinone] 1 subunit C2

14.5b subunit of the NADH-ubiquinone dehydrogenase complex	CI-B14.5b
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2	NADH-ubiquinone oxidoreductase subunit B14.5b
complex I-B14.5b

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09156	NDUFC2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown
HY-RS21897	Ndufc2 Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Ndufc2	NCBI	NCBI:4718

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