2. Gene
  3. Pdgfd - platelet derived growth factor D Gene

Pdgfd - platelet derived growth factor D Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Scdgfb; rSCDGF-B

Gene ID: 66018 | Gene type: protein coding

About Pdgfd

Summary

Predicted to enable platelet-derived growth factor receptor binding activity. Involved in several processes, including cellular response to growth factor stimulus; positive regulation of cell migration; and positive regulation of cell population proliferation. Located in extracellular space. Used to study glomerulonephritis and mesangial proliferative glomerulonephritis. Biomarker of liver cirrhosis; mesangial proliferative glomerulonephritis; and myocardial infarction. Human ortholog(s) of this gene implicated in prostatic hypertrophy. Orthologous to human PDGFD (platelet derived growth Factor D). [provided by Alliance of Genome Resources, Apr 2022]

Pdgfd Products(1)

mRNA Protein Name
NM_023962.3 NP_076452.1 platelet-derived growth factor D precursor
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in cellular response to hydrogen peroxide IEP
IEP: Inferred from expression pattern
16189269 RGD
involved in cellular response to platelet-derived growth factor stimulus IEP
IEP: Inferred from expression pattern
16039137 RGD
involved in cellular response to transforming growth factor beta stimulus IMP
IMP: Inferred from mutant phenotype
23585135 RGD
involved in positive regulation of fibroblast proliferation IDA
IDA: Inferred from direct assay
21866094 RGD
involved in positive regulation of glomerular mesangial cell proliferation IMP
IMP: Inferred from mutant phenotype
12937299 RGD
involved in positive regulation of monocyte extravasation IMP
IMP: Inferred from mutant phenotype
12937299 RGD
involved in positive regulation of smooth muscle cell chemotaxis IMP
IMP: Inferred from mutant phenotype
15752751 RGD
involved in positive regulation of smooth muscle cell proliferation IDA
IDA: Inferred from direct assay
15752751 RGD
Cellular Component GO Annotation Evidence Reference Source
located in extracellular space IDA
IDA: Inferred from direct assay
17397961 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

platelet-derived growth factor D

iris-expressed growth factor

platelet-derived growth factor, D polypeptide

spinal cord-derived growth factor B

spinal-cord derived growth factor-B protein

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10253 PDGFD Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS18294 Pdgfd Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS24772 Pdgfd Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Pdgfd NCBI NCBI:80310
Mus musculus Pdgfd NCBI NCBI:71785