2. Gene
  3. Cldn5 - claudin 5 Gene

Cldn5 - claudin 5 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 65131 | Gene type: protein coding

About Cldn5

Summary

Predicted to enable identical protein binding activity. Involved in myelination and response to ethanol. Located in Schmidt-Lanterman incisure; lateral plasma membrane; and paranode region of axon. Biomarker of middle cerebral artery infarction. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human CLDN5 (Claudin 5). [provided by Alliance of Genome Resources, Apr 2022]

Cldn5 Products(1)

mRNA Protein Name
NM_031701.2 NP_113889.1 claudin-5
Gene Ontology
  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Reference Source
involved in myelination IPI
IPI: Inferred from physical interaction
12403818 RGD
involved in response to ethanol IEP
IEP: Inferred from expression pattern
17889313 RGD
Cellular Component GO Annotation Evidence Reference Source
located in Schmidt-Lanterman incisure IDA
IDA: Inferred from direct assay
12403818 RGD
located in lateral plasma membrane IDA
IDA: Inferred from direct assay
19929946 RGD
located in paranode region of axon IDA
IDA: Inferred from direct assay
12403818 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

claudin-5

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-W014507 9,10-Phenanthrenequinone Inhibitor 99.95% Unkown
HY-RS02773 CLDN5 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22444 Cldn5 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28967 Cldn5 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cldn5 NCBI NCBI:7122