2. Gene
  3. Bid - BH3 interacting domain death agonist Gene

Bid - BH3 interacting domain death agonist Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 64625 | Gene type: protein coding

About Bid

Summary

Predicted to enable ubiquitin protein Ligase binding activity. Involved in several processes, including positive regulation of Autophagy in response to ER overload; release of cytochrome c from mitochondria; and response to ischemia. Located in cytosol and mitochondrion. Used to study pre-malignant neoplasm. Human ortholog(s) of this gene implicated in pancreatic Cancer. Orthologous to human BID (BH3 interacting domain death agonist). [provided by Alliance of Genome Resources, Apr 2022]

Bid Products(1)

mRNA Protein Name
NM_022684.2 NP_073175.1 BH3-interacting domain death agonist
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
12871587 RGD
Biological Process GO Annotation Evidence Reference Source
involved in glial cell apoptotic process IEP
IEP: Inferred from expression pattern
18931364 RGD
involved in positive regulation of autophagy in response to ER overload IMP
IMP: Inferred from mutant phenotype
25772147 RGD
involved in release of cytochrome c from mitochondria IDA
IDA: Inferred from direct assay
18252800 RGD
involved in response to estradiol IEP
IEP: Inferred from expression pattern
20803709 RGD
involved in response to ischemia IEP
IEP: Inferred from expression pattern
11934844 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

BH3-interacting domain death agonist

apoptotic death agonist BID

desmocollin type 4

p22 BID

Related Agents

Approval
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-B0493 Niflumic acid Inhibitor 99.61% Unkown
HY-B0493R Niflumic acid (Standard) Inhibitor / Unkown
Pre-clinical Phase
Bioactive Molecules (15)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-10510 BI-D1870 99.43% Unkown
HY-103661 BI-6C9 Inhibitor 98.47% Unkown
HY-18601 (±)-BI-D Inhibitor 98.06% Unkown
HY-125305 Z-AEVD-FMK Inhibitor ≥95.0% Unkown
HY-123244 YC137 / Unkown
HY-162642 Bfl-1-IN-3 Inhibitor / Unkown
HY-P10614 Bid BH3 peptide / Unkown
HY-P5325 Bid BH3 (80-99) / Unkown
HY-P5325F Bid BH3 (80-99), FAM labeled / Unkown
HY-P5327 r8 Bid BH3 / Unkown
HY-RS01502 BID Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-121683 (E)-2-Hexadecenal / Unkown
HY-167881 MLS-0053105 Inhibitor / Unkown
HY-RS16655 Bid Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23090 Bid Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Bid NCBI NCBI:637
Mus musculus Bid NCBI NCBI:12122