2. Gene
  3. Ppib - peptidylprolyl isomerase B Gene

Ppib - peptidylprolyl isomerase B Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as CypB; Scylp

Gene ID: 64367 | Gene type: protein coding

About Ppib

Summary

Predicted to enable RNA polymerase binding activity; cyclosporin A binding activity; and peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in several processes, including neutrophil chemotaxis; positive regulation by host of viral genome replication; and protein stabilization. Located in smooth endoplasmic reticulum. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 9. Orthologous to human PPIB (peptidylprolyl isomerase B). [provided by Alliance of Genome Resources, Apr 2022]

Ppib Products(1)

mRNA Protein Name
NM_022536.2 NP_071981.1 peptidyl-prolyl cis-trans isomerase B precursor
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
22665516 RGD
Cellular Component GO Annotation Evidence Reference Source
located in smooth endoplasmic reticulum IDA
IDA: Inferred from direct assay
22665516 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

peptidyl-prolyl cis-trans isomerase B

CYP-S1

PPIase B

S-cyclophilin

S-cyclophylin

cyclophilin B

rotamase B

Ppib Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Reference
Intra
Ppib P24368 Pdia4 Rattus norvegicus P38659
Pull Down
22665516
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10947 PPIB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18494 Ppib Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24976 Ppib Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ppib NCBI NCBI:5479