2. Gene
  3. Trpc3 - transient receptor potential cation channel, subfamily C, member 3 Gene

Trpc3 - transient receptor potential cation channel, subfamily C, member 3 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Trrp3; TrpC3c

Gene ID: 60395 | Gene type: protein coding

About Trpc3

Summary

Enables calcium activated cation channel activity. Predicted to be involved in several processes, including metal ion transport; positive regulation of cardiac muscle hypertrophy in response to stress; and response to ATP. Predicted to be integral component of membrane. Predicted to be part of cation channel complex. Predicted to be integral component of plasma membrane. Human ortholog(s) of this gene implicated in cerebellar ataxia type 41. Orthologous to human TRPC3 (transient receptor potential cation channel subfamily C member 3). [provided by Alliance of Genome Resources, Apr 2022]

Trpc3 Products(1)

mRNA Protein Name
NM_021771.2 NP_068539.2 short transient receptor potential channel 3
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables calcium-activated cation channel activity IDA
IDA: Inferred from direct assay
10984475 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

short transient receptor potential channel 3

ion channel protein

trp-related protein 3

Related Agents

Clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Phase
HY-P2141 TRV-120027 Agonist 98.11% Phase 2
HY-P2141A TRV-120027 TFA Agonist 99.69% Phase 2
Pre-clinical Phase
Bioactive Molecules (20)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-111925 BI-749327 Antagonist 99.91% Unkown
HY-108465 Pyr3 Inhibitor 99.90% Unkown
HY-111098 GSK1702934A Agonist 99.11% Unkown
HY-101507 Zerencotrep Inhibitor 99.47% Unkown
HY-19408 Pyr10 Inhibitor 99.95% Unkown
HY-12504 Pyr6 Inhibitor 98.61% Unkown
HY-138668 JW-65 Inhibitor 99.05% Unkown
HY-111527 PPZ2 99.92% Unkown
HY-161766 L687 Activator / Unkown
HY-120818 TRPC3/6-IN-3 / Unkown
HY-121519 GSK2332255B Antagonist / Unkown
HY-126424 OptoDArG / Unkown
HY-133528 OptoBI-1 Agonist / Unkown
HY-153455 TRPC3/6-IN-2 Inhibitor / Unkown
HY-162090 TRPC antagonist 1 Antagonist / Unkown
HY-172600 TRPC6 antagonist-1 Antagonist / Unkown
HY-RS15105 TRPC3 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-147357 TRPC3/6-IN-1 Inhibitor / Unkown
HY-RS16759 Trpc3 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS23198 Trpc3 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Trpc3 NCBI NCBI:7222